Therapeutically Relevant Multiple Pathways Database

         Basically, a disease processes will often occur between protein in some different pathways. These different protein has been used for the separately for treating a particular diseases. In order to facilitate mechanistic study of the drugs actions and more comprehensive understanding between different target of the same disease, therapeutically relevant multiple pathways database is developed. Furthermore, these database also contain detail about non-target proteins and natural small molecule involved in these same pathways which may provide useful hint for searching new therapeutic targets. On the other hand, these information also facilitate the understanding of how therapeutic targets interact with other molecules in performing specific tasks. 

Figure 1: The above picture showing the homepage of the Therapeutically Relevant Multiple Pathways Database

       Additionally, these database contain about 11 entries of multiple pathways, 97 entries of individual pathway, 120 targets covering 72 diseases conditions together with 120 steps of drugs directed at each of the target. 

Figure 2 : The above picture showing lipid , carbohydrate metabolism in adipose tissue cells.

                Besides that,  an additional information also available in this database such as protein name, synonyms, Swissprot Ac number, species, gene name and location, protein sequence and gene sequence as well as potential therapeutic implications while applicable. Cross-links to other databases are provided which include Genecard, GDB, Locuslink, NCBI, KEGG, OMIM and SwissProt to facilitate the access of more detailed information about various aspects of the particular target or non-target protein.